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Francis Y. Lee, MD, PhD
Curriculum Vitae
| CLINICAL INTERESTS |
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- Bone and Soft Tissue Tumors in Children and Adults
- Complex Limb Deformities & Limb Lengthening
- Children’s Osteoporosis, Syndromes and Bone Disease
- Congenital and Acquired Hip Disorders
- Spine Deformity (Scoliosis)
- Pediatric Foot Construction
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| BOARD CERTIFICATIONS |
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American Board of Orthopaedic Surgery
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| LICENSURE |
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New York
New Jersey
Massachusetts
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| EDUCATION |
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Fellowship
1998-1999 |
The Hospital for Sick Children
University of Toronto
Pediatric Orthopaedic Surgery
Clinical Fellow |
1997-1998 |
Harvard Medical School
Mass General & Childrens Hospital
Orthopaedic Oncology
Clinical Fellow |
| 1996 |
New Jersey Medical School
Newark, New Jersey
Orthopaedic Research Fellow |
| 1995 |
Mount Sinai School of Medicine
New York, New York
Orthopaedic Research Fellow
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Residency
1992-1997 |
New Jersey Medical School
Newark, New Jersey
Department of Orthopaedic Surgery |
| 1987-1992 |
Seoul National University Hospital
Seoul, Korea
Department of Orthopaedic Surgery |
Graduate
1993 |
Seoul National University
Orthopaedic Science
Seoul, Korea
M.S., Ph.D. |
Medical School
1986 |
Seoul National University
Seoul, Korea
M.D. |
Undergraduate
1982 |
Seoul National University
Seoul, Korea
B.S. |
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| CURRENT HOSPITAL & ACADEMIC APPOINTMENTS |
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08/01/1999- 07/31/05
Assistant Professor
Department of Orthopaedic Surgery
Columbia University, New York
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08/01/1999 – Present
Chief of Tumor and Bone Disease Service
Department of Orthopaedic Surgery
Columbia University, New York
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09/01/2003 - Present
Director of Center for Orthopaedic Research
Department of Orthopaedic Surgery
Columbia University, New York
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08/01/2006- Present
Associate Professor of Clinical Orthopaedic Surgery
Columbia University, New York
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07/01/2007 – Present
Vice Chairman for Research
Department of Orthopaedic Surgery
Columbia University, New York
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| PROFESSIONAL ORGANIZATIONS AND SOCIETIES |
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Grant Reviewer, NIH Skeletal Biology and Skeletal Regeneration Study Section (2007)
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AAOS Leadership Fellow (2007 – Present)
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Grant Reviewer, Musculoskeletal Transplantation Foundation (2006 – Present)
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Grant Reviewer, Orthopaedic Research and Education Foundation (2006 – Present)
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Member, American Orthopaedic Association (2006 – Present)
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Member, American Academy of Orthopaedic Surgeon, Evaluation Committee (2005 – Present)
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Member, American Academy of Orthopaedic Surgeon, Basic Science Evaluation Subcommittee / Basic Science Committee for Orthopaedic In-Training Examination (2004 – Present)
- Musculoskeletal Tumor Society , U.S.A. (2003 - )
- Member, American Academy of Orthopaedic Surgeons (2001 – Present)
- American Medical Associatio
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Member, Orthopaedic Research Society (1997 – Present)
- American Society for Bone and Mineral Research
- Irving Comprehensive Cancer Center
- New York Academy of Medicine
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Member, New York Academy of Science(1996 – Present)
- International Bone and Mineral Society
- American Academy of Orthopaedic Surgery, Basic Science Evaluation Subcommitee
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| RECENT HONORS |
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| RESEARCH GRANTS AND AWARDS |
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Present Research Support (Principal Investigator: Francis Y. Lee, M.D.)
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Orthopaedic Research and Education Foundation Grant
Role: Principal Investigator
Career Development Award (Peer-Reviewed)
Period: July 1st, 2006 – June 30th, 2009
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National Institute of Health (NIH)
Role: Principal Investigator
National Institute of Biomedical Imaging and Biomedical Engineering (NIBIB)
NIH R01EB006834-01
Title: Mechanobiological Mechanism of Inflammatory Bone Loss
Period: June 1st, 2007 – May 31st, 2011
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Columbia University Venture Fund
Role: Principal Investigator
Title: Innovative Sarcoma Research (Stem Cell-based Delivery of siRNA to Sarcoma Cells)
Period: January 1st, 2007 – December 31st, 2007
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Unrestricted Research Grant (Donor: David E. Shaw, Ph.D)
Role: Principal Investigator
Period: November 25, 2005 – Present
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Orthopaedic Research and Education Foundation Grant
Role: Mentor (Co-PI)
Resident Research Grant (PI: Sam K. Cho, M.D., Orthopaedic Resident)
Title: The role of ERK signaling in titanium-induced inflammatory bone loss
Period: July 1st, 2007 – June 30th, 2008
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Orthopaedic Science Research Foundation (OSRF)
Role: Principal Investigator
Title: In vivo Biomolecular Imaging Core Grant
Period: July 1st, 2007 – June 30th, 2008
Past Research Support (Principal Investigator: Francis Y. Lee, M.D.)
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Orthopaedic Research & Education Foundation
Role: Principal Investigator
Resident Research Award / Research Grant (Peer-Reviewed)
Title: The fate of chondrocyte during fracture healing
Period: January 1st, 1995 – December 31st, 1995
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American Fracture Association
Role: Principal Investigator
Title: The effect of nicotine on fracture healing
Period: July 1st, 1996 – December 31st, 2006
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National Orthopaedic Surgery Fellowship Foundation
Role: Principal Investigator
Title: The effect of rhBMP-2 on allograft fracture repair
Period: January 1st, 1998 – June 30th, 1998
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Hospital for Sick Children Start-up Research Grant
Role: Principal Investigator
Title: Vitamin D3 pathway activation in chondrosarcoma
Period: January 1st, 1999 – June 30th, 1999
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American Cancer Society Pilot Award
Role: Principal Investigator
Title: Molecular Pathways in Cartilage Tumors
Period: January 1st, 2002 – December 31st, 2002
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Woman-at-Risk, Breast Cancer Program
Role: Principal Investigator
Title: Molecular mechanisms of osteolytic metastatic breast cancer
Period: July 1st, 2002 – June 30th, 2003
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Howmedica, Rutherford, NJ
Role: Principal Investigator
Title: Developing Novel Implants
Period: January 1st, 2003 – June 30th, 2004
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Aircast Foundation Research Grant
Role: Principal Investigator
Title: Targeting Cell Survival Genes of Chondrosarcoma (Peer Reviewed)
Period: January 1st, 2005 – December 31st, 2006
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Musculoskeletal Transplant Foundation
Role: Principal Investigator
Title: The Beneficial Effect of Topical Bisphosphonate on Trabecular Bone Allograft
Period: Jan 1, 2005 – Dec 31, 2005
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Orthopaedic Research and Education Foundation
Role: Principal Investigator
Title: SDF-1 Regulation in Osteoclastogenesis
Period: July 1, 2004-June 30, 2006
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TissueGene, Inc., Gaithersburg, MD
Role: Principal Investigator
Sponsored Research Grant through Columbia University
Title: Gene Expression Profiling of Cartilage
Period: 2003-2006
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Orthopaedic Research and Education Foundation Grant
Role: Mentor
Resident Research Grant (PI: Sanjeev Suratwala, M.D., Orthopaedic Resident)
Title: The role of topical bisphosphonate on orthopaedic implants
Period: Jan 1st, 2006 – June 30th, 2006
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Orthopaedic Research and Education Foundation Grant
Role: Mentor
Resident Research Grant (PI: Steve Storer, M.D., Orthopaedic Resident)
Title: The role of bisphosphonate on allograft bone healing
Period: Jan 1st, 2004 – June 30th, 2004
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Orthopaedic Science Research Foundation
Role: Center Director
Center for Orthopaedic Research Infrastructure Grant
Period: 2004 – 2006
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| PEER-REVIEWED PUBLICATIONS
(In Chronological Order) |
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CLINICAL STUDIES
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Seo, S.; Adelmir, A.; Minematsu, H.; and Lee, F.: ERK SIGNALING REGULATES M-CSF EXPRESSION INDUCED BY TITANIUM NANOPARTICLES IN MC3T3-E1 MURINE CALVARIAL PRE-OSTEOBLASTIC CELLS. Ann N Y Acad Sci, (In Press), 2007.
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Minematsu, H.; Seo, S.; Adelmir, A.; and Lee, F.: CALCINEURIN/NFATC1 AXIS REGULATES UHMWPE WEAR PARTICLE-INDUCED CYTOKINE EXPRESSION IN MACROPHAGES. Ann N Y Acad Sci, (In Press) 2007.
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Lowenstein, J. E.; Matsumoto, H.; Vitale, M. G.; Weidenbaum, M.; Gomez, J. A.; Lee, F. Y.; Hyman, J. E.; and Roye, D. P., Jr.: Coronal and sagittal plane correction in adolescent idiopathic scoliosis: a comparison between all pedicle screw versus hybrid thoracic hook lumbar screw constructs. Spine, 32(4): 448-52, 2007.
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Kim, D. W.; Seo, S. W.; Cho, S. K.; Chang, S. S.; Lee, H. W.; Lee, S. E.; Block, J. A.; Hei, T. K.; and Lee, F. Y.: Targeting of cell survival genes using small interfering RNAs (siRNAs) enhances radiosensitivity of Grade II chondrosarcoma cells. J Orthop Res, 25(6): 820-8, 2007.
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Adelmir, A.; Kim, D.; and Lee, F.: Calcineurin/NFATc axis mediated fluid shear stress-induced COX-2 expression in human mesenchymal cells. Ann N Y Acad Sci, [Epub ahead of print], 2007.
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Vitale, M. A.; Choe, J. C.; Sesko, A. M.; Hyman, J. E.; Lee, F. Y.; Roye, D. P., Jr.; and Vitale, M. G.: The effect of limb length discrepancy on health-related quality of life: is the '2 cm rule' appropriate? J Pediatr Orthop B, 15(1): 1-5, 2006.
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Lee, F. Y.; Sinicropi, S. M.; Lee, F. S.; Vitale, M. G.; Roye, D. P., Jr.; and Choi, I. H.: Treatment of congenital pseudarthrosis of the tibia with recombinant human bone morphogenetic protein-7 (rhBMP-7). A report of five cases. J Bone Joint Surg Am, 88(3): 627-33, 2006.
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Kim, Y. S.; Bigliani, L. U.; Fujisawa, M.; Murakami, K.; Chang, S. S.; Lee, H. J.; Lee, F. Y.; and Blaine, T. A.: Stromal cell-derived factor 1 (SDF-1, CXCL12) is increased in subacromial bursitis and downregulated by steroid and nonsteroidal anti-inflammatory agents. J Orthop Res, 24(8): 1756-64, 2006.
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Kim, D. W. et al.: Mechanical loading differentially regulates membrane-bound and soluble RANKL availability in MC3T3-E1 cells. Ann N Y Acad Sci, 1068: 568-72, 2006.
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Yu, J.; Chang, S. S.; Suratwala, S.; Chung, W. S.; Abdelmessieh, P.; Lee, H. J.; Yang, J.; and Lee, F. Y.: Zoledronate induces apoptosis in cells from fibro-cellular membrane of unicameral bone cyst (UBC). J Orthop Res, 23(5): 1004-12, 2005.
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Yoon, A. J.; Parisien, M.; Feldman, F.; and Young-In Lee, F.: Extranodal Rosai-Dorfman disease of bone, subcutaneous tissue and paranasal sinus mucosa with a review of its pathogenesis. Skeletal Radiol, 34(10): 653-7, 2005.
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Vitale, M. G.; Roye, E. A.; Choe, J. C.; Hyman, J. E.; Lee, F. Y.; and Roye, D. P., Jr.: Assessment of health status in patients with cerebral palsy: what is the role of quality-of-life measures? J Pediatr Orthop, 25(6): 792-7, 2005.
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Vitale, M. G.; Choe, J. C.; Vitale, M. A.; Lee, F. Y.; Hyman, J. E.; and Roye, D. P., Jr.: Patient-based outcomes following clubfoot surgery: a 16-year follow-up study. J Pediatr Orthop, 25(4): 533-8, 2005.
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Storer, S. K.; Vitale, M. G.; Hyman, J. E.; Lee, F. Y.; Choe, J. C.; and Roye, D. P., Jr.: Correction of adolescent idiopathic scoliosis using thoracic pedicle screw fixation versus hook constructs. J Pediatr Orthop, 25(4): 415-9, 2005.
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Liao, T. S. et al.: Recruitment of osteoclast precursors by stromal cell derived factor-1 (SDF-1) in giant cell tumor of bone. J Orthop Res, 23(1): 203-9, 2005.
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Lee, F. Y.; Schoeb, J. S.; Yu, J.; Christiansen, B. D.; and Dick, H. M.: Operative lengthening of the humerus: indications, benefits, and complications. J Pediatr Orthop, 25(5): 613-6, 2005.
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Lee, F. Y. et al.: mu-Calpain regulates receptor activator of NF-kappaB ligand (RANKL)-supported osteoclastogenesis via NF-kappaB activation in RAW 264.7 cells. J Biol Chem, 280(33): 29929-36, 2005.
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Blaine, T. A. et al.: The molecular pathophysiology of subacromial bursitis in rotator cuff disease. J Shoulder Elbow Surg, 14(1 Suppl S): 84S-89S, 2005.
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Young-In Lee, F.; Hornicek, F. J.; Dick, H. M.; and Mankin, H. J.: Synovial chondromatosis of the foot. Clin Orthop Relat Res, (423): 186-90, 2004.
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Ugwonali, O. F.; Lomas, G.; Choe, J. C.; Hyman, J. E.; Lee, F. Y.; Vitale, M. G.; and Roye, D. P., Jr.: Effect of bracing on the quality of life of adolescents with idiopathic scoliosis. Spine J, 4(3): 254-60, 2004.
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Roposch, A.; Bhaskar, A. R.; Lee, F.; Adedapo, S.; Mousny, M.; and Alman, B. A.: Orthopaedic manifestations of Brachmann-de Lange syndrome: a report of 34 patients. J Pediatr Orthop B, 13(2): 118-22, 2004.
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Lee, F. Y.; Yu, J.; Chang, S. S.; Fawwaz, R.; and Parisien, M. V.: Diagnostic value and limitations of fluorine-18 fluorodeoxyglucose positron emission tomography for cartilaginous tumors of bone. J Bone Joint Surg Am, 86-A(12): 2677-85, 2004.
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Delloye, C.; Suratwala, S. J.; Cornu, O.; and Lee, F. Y.: Treatment of allograft nonunions with recombinant human bone morphogenetic proteins (rhBMP). Acta Orthop Belg, 70(6): 591-7, 2004.
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Chang, S. S.; Suratwala, S. J.; Jung, K. M.; Doppelt, J. D.; Zhang, H. Z.; Blaine, T. A.; Kim, T. W.; Winchester, R. J.; and Lee, F. Y.: Bisphosphonates may reduce recurrence in giant cell tumor by inducing apoptosis. Clin Orthop Relat Res, (426): 103-9, 2004.
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Vitale, M. G.; Choe, J. C.; Hwang, M. W.; Bauer, R. M.; Hyman, J. E.; Lee, F. Y.; and Roye, D. P., Jr.: Use of ketorolac tromethamine in children undergoing scoliosis surgery. an analysis of complications. Spine J, 3(1): 55-62, 2003.
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Lee, F. Y., and Chapman, C. B.: In situ pinning of hip for stable slipped capital femoral epiphysis on a radiolucent operating table. J Pediatr Orthop, 23(1): 27-9, 2003.
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Osgood, G. M.; Lee, F. Y.; Parisien, M. V.; and Ruzal-Shapiro, C.: Magnetic resonance imaging depiction of tight iliotibial band in melorheostosis associated with severe external rotation deformity, limb shortening and patellar dislocation in planning surgical correction. Skeletal Radiol, 31(1): 49-52, 2002.
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Lee, F. Y.; Zawadsky, M.; Parisien, M.; Ho, M.; Murty, V. V.; Jayaraman, T.; and Dick, H. M.: Novel translocation (9;12)(q22;q24) in secondary chondrosarcoma arising from hereditary multiple exostosis. Cancer Genet Cytogenet, 132(1): 68-70, 2002.
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Lee, F. Y.; Storer, S.; Hazan, E. J.; Gebhardt, M. C.; and Mankin, H. J.: Repair of bone allograft fracture using bone morphogenetic protein-2. Clin Orthop Relat Res, (397): 119-26, 2002.
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Patari, S. K.; Lee, F. Y.; and Behrens, F. F.: Coronal split fracture of the proximal tibia epiphysis through a partially closed physis: a new fracture pattern. J Pediatr Orthop, 21(4): 451-5, 2001.
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Lee, F.; Keel, S. B.; Gebhardt, M. C.; and Rosenthal, D. I.: Intra-articular lipoma with osteochondroid metaplasia in the knee joint. Skeletal Radiol, 30(4): 230-3, 2001.
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Ahmad, C. S., and Lee, F. Y.: An all-arthroscopic soft-tissue balancing technique for lateral patellar instability. Arthroscopy, 17(5): 555-7, 2001.
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Ramappa, A. J.; Lee, F. Y.; Tang, P.; Carlson, J. R.; Gebhardt, M. C.; and Mankin, H. J.: Chondroblastoma of bone. J Bone Joint Surg Am, 82-A(8): 1140-5, 2000.
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Margau, R.; Babyn, P.; Cole, W.; Smith, C.; and Lee, F.: MR imaging of simple bone cysts in children: not so simple. Pediatr Radiol, 30(8): 551-7, 2000.
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Lee, F. Y.; Hazan, E. J.; Gebhardt, M. C.; and Mankin, H. J.: Experimental model for allograft incorporation and allograft fracture repair. J Orthop Res, 18(2): 303-6, 2000.
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Lee, F. Y.; Montgomery, M.; Hazan, E. J.; Keel, S. B.; Mankin, H. J.; and Kattapuram, S.: Recurrent giant-cell tumor presenting as a soft-tissue mass. A report of four cases. J Bone Joint Surg Am, 81(5): 703-7, 1999.
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Lee, F. Y.; Mankin, H. J.; Fondren, G.; Gebhardt, M. C.; Springfield, D. S.; Rosenberg, A. E.; and Jennings, L. C.: Chondrosarcoma of bone: an assessment of outcome. J Bone Joint Surg Am, 81(3): 326-38, 1999.
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Lee, F. Y.; Rho, J. Y.; Harten, R., Jr.; Parsons, J. R.; and Behrens, F. F.: Micromechanical properties of epiphyseal trabecular bone and primary spongiosa around the physis: an in situ nanoindentation study. J Pediatr Orthop, 18(5): 582-5, 1998.
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Lee, F. Y.; Hornicek, F. J.; Hazan, E. J.; Kloen, P.; Wolfe, M. A.; and Mankin, H. J.: Reconstruction of the shoulder joint using an acetabular allograft. A report of two cases. Clin Orthop Relat Res, (357): 116-21, 1998.
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Lee, F. Y.; Gebhardt, M. C.; Keel, S. B.; and Rosenthal, D. I.: A discrete soft tissue mass in the distal thigh of a 29-year-old man. Clin Orthop Relat Res, (357): 247-50, 255-6, 1998
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Lee, F. Y.; Choi, Y. W.; Behrens, F. F.; DeFouw, D. O.; and Einhorn, T. A.: Programmed removal of chondrocytes during endochondral fracture healing. J Orthop Res, 16(1): 144-50, 1998.
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Benevenia, J.; Lee, F. Y.; Buechel, F.; and Parsons, J. R.: Pathologic supracondylar fracture due to osteolytic pseudotumor of knee following cementless total knee replacement. J Biomed Mater Res, 43(4): 473-7, 1998.
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Harten, R. D., Jr.; Lee, F. Y.; Zimmerman, M. C.; Hurowitz, E.; Arakal, R.; and Behrens, F. F.: Regional and temporal changes in the acoustic properties of fracture callus in secondary bone healing. J Orthop Res, 15(4): 570-6, 1997.
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Seong, S. C.; Matsumura, T.; Lee, F. Y.; Whelan, M. C.; Li, X. Q.; and Trippel, S. B.: Insulin-like growth factor I regulation of Swarm rat chondrosarcoma chondrocytes in culture. Exp Cell Res, 211(2): 238-44, 1994.
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Kim, Y. M.; Lee, S. H.; Lee, F. Y.; Koo, K. H.; and Cho, K. H.: Morphologic and biomechanical study of avascular necrosis of the femoral head. Orthopedics, 14(10): 1111-6, 1991.
BOOKS AND CHAPTERS
- Carol Morris, Lee FY and Gebhardt MC. Benign Bone Tumors, Chapter, Operative Orthopaedic Surgery, Ed. Chapman M, Williams and Wilkins, 2000.
- Lee FY and Lee HK. Basic science in musculoskeletal tumor, Chapter, Musculoskeletal Oncology, Ed. Lee HK, 1996, Korea.
- Hyman J, Lee FY, Roye DP. Orthopaedic Surgery, Chapter, Pediatric Secrets, Ed, 200.
- Seo SW, F Remotti, Lee FY: Chondrosarcoma, Orthopaedic Knowledge Update, Musculoskeletal Oncology (In Press).
- Seo SW, Moon YL, Lee FY: Benign Cystic Lesions. Essentials of Orthopaedic Surgery, (In Preparation)
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| SELECTED PRESENTATIONS
AND POSTERS (last 5 years) |
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- NFAT REGULATES LPS-INDUCED M-CSF EXPRESSION IN PRE-OSTEOBLASTIC CELLS. 53RD Annual Meeting of Orthopaedic Research Society, San Diego, 2007.
- CALCINEURIN/NFATC1 AXIS REGULATES UHMWPE WEAR PARTICLE-INDUCED CYTOKINE EXPRESSION IN BOTH PREOSTEOBLASTIC MC3T3-E1 CELLS AND RAW 264.7 CELLS. 53RD Annual Meeting of Orthopaedic Research Society, San Diego, 2007.
- NFAT AND ERK SIGNALING REGULATE M-CSF EXPRESSION INDUCED BY TITANIUM NANOPARTICLES IN MC3T3-E1 MURINE CALVARIAL PRE-OSTEOBLASTIC CELLS. 53RD Annual Meeting of Orthopaedic Research Society, San Diego, 2007.
- Kim, D W; Seo, S W; Ahn, J M; Lee, S E; Lee, H-J.; Lee, F Y: THE CALCINEURIN / NUCLEAR FACTOR OF ACTIVATED T CELL (NFAT) AXIS MEDIATES FLUID SHEAR STRESS-INDUCED COX-2 EXPRESSION IN MC3T3-E1 CELLS. 52ND Annual Meeting of Orthopaedic Research Society, Chicago, 2006.
- Kim, D W; Lee, S E; Seo, S W; Cho, S; Hei, T; Lee, F Y: DUAL SILENCING OF Bcl-2 and Bcl-XL GENES ENHANCES RADIOSENSITIVITY IN CHONDROSARCOMA. 52ND Annual Meeting of Orthopaedic Research Society, Chicago, 2006.
- Lee, H.-J., Kim, DW,*Kim, A., Tolchin, B., Ahn, JM, and Lee, FY: REGULATION OF THE RANKL/OPG RATIO BY FLUID SHEAR STRESS in MC3T3-E1 CELLS. 52ND Annual Meeting of Orthopaedic Research Society, Chicago, 2006.
- Suratwala, S J; Gardner, T R; Seo S W; Ahn J M; Park, S H; Yeh, J K; Lee, F Y: BISPHOSPHONATE/HYDROXYAPATITE COATED FEMORAL NAILS PRESERVE PERIPROSTHETIC BONE MASS AND EXHIBIT HIGHER FAILURE LOAD IN A RODENT OSTEOLYSIS MODEL. 52ND Annual Meeting of Orthopaedic Research Society, Chicago, 2006.
- Fujisawa M; Ankem HK; Moon YL; Minematsu H; Chang S-S; Lee HJ; Lee FY: Bigliani LU and Blaine TA: MECHANICAL STRAIN INDUCED ACTIVATION OF IL-6, COX-2 AND SDF-1 IN SUBACROMIAL BURSAL CELLS INVOLVES ERK (MAPK), P38, JNK AND NF-kb SIGNALING PATHWAYS. 52ND Annual Meeting of Orthopaedic Research Society, Chicago, 2006.
- Fujisawa M; Ankem HK; Moon YL; Minematsu H; Chang S-S; Lee HJ; Lee FY; Bigliani LU and Blaine TA: MECHANICAL STRAIN INDUCES ACTIVATION OF INFLAMMATORY CYTOKINES IN SUBACROMIAL BURSAL CELLS: AN IN VITRO MODEL FOR SUBACROMIAL IMPINGEMENT. 52ND Annual Meeting of Orthopaedic Research Society, Chicago, 2006.
- Tolchin BD; Birk DM; Chang SS; Chung W; Cho SK; Kwon A; Lee HJ; Lee FY: MECHANICAL LOADING ALTERS THE EXPRESSION OF OSTEOGENIC AND OSTEOCLASTOGENIC REGULATORS IN VITRO 51st Annual Meeting of Orthopaedic Research Society, 2005.
- Karmin, J; Chang, S-S; Shrivastana, N; Lin S; Wang, D; Blaine, TA; Bigliani, LU; Lee FY; Lee, H-J: Small Interfering RNA (siRNA) Targeting Receptor for Advanced Glycation End Products (RAGE) Downregulates Stromal Cell Derived Factor 1 (SDF-1) in Rheumatoid Arthritis Cells. Annual Meeting of Orthopaedic Research Society, 2005.
- Fujisawa M; Kim, Y-S; Murakami, K; Chang, S-S; Lee, H-J; Lee FY; Bigliani L; Blaine TA: EXPRESSION PROFILE OF MATRIX/ADHESION MOLECULESIN SUBACROMIAL BURSITIS. 51st Annual Meeting of Orthopaedic Research Society, 2005.
- Kim, D W; Abdelmessieh, P; Lin, S; Wang, D; Fujisawa M; Chang, S S; Lee, H J; Lee F Y: Neoplastic Chondrocytes of Chondrosarcoma Activate Bcl-2 Cell Survival Machinery and Inhibitors of Apoptosis Under Nutritional Deprivation. 51st Annual Meeting of Orthopaedic Research Society, 2005.
- Hong, D; Chung, WS; Shrivastava, N; Bigliani, LU; Lee, FY;Lee HJ: CALPAIN IS A MEDIATOR OF RANKL INDUCED OSTEOCLASTOGENESIS OF MURINE MACROPHAGES IN VITRO. 51st Annual Meeting of Orthopaedic Research Society, 2005.
- Fujisawa M, Kim Y-S, Murakami K, Abdelmessieh P, Chang, S-S, Lee, H-J, Blaine TA, and Lee FY; FUNCTION OF A HECT DOMAIN UBIQUITIN LIGASE IN OSTEOBLAST DIFFERENTIATION. 51st Annual Meeting of Orthopaedic Research Society, 2005.
- Birk DM; Tolchin BD; Chang SS; Shrivastana N; Lee HJ; Blaine TA; Lee FY: The effect of mechanical strain on Osteoclastogenesis in RAW 264.7 Cells in Vitro. 51st Annual Meeting of Orthopaedic Research Society, 2005.
- Kim YS, Lee HJ, Chang SS, Lee FY, Bigliani LU, Blaine TA: SDF-1 expression in shoulder bursitis. 51st Annual Meeting of Orthopaedic Research Society, 2005.
- Suratwala, S; Sinicropi. S; Lee, H J; Lee, F S, Vitale, M G; Roye, D P; Choi, I H, Delloye, C; Lee FY: Recombinant Human Bone Morphogenetic Proteins Are Not Sufficient To Induce Healing in Difficult Human Nonunions. 51st Annual Meeting of Orthopaedic Research Society, 2005.
- Suratwala S, Storer SK, Martin G, Yeh JK, Lee FY: THE EFFECT OF BISPHOSPHONATES ON ALLOGRAFT INCORPORATION. Annual Meeting of American Academy of Orthopaedic Surgeons, 2005
- Lee FY, Suratwala, S, Yu J: TREATMENT OF AGGRESSIVE OSTEOLYTIC BENIGN BONE LESIONS WITH TOPICAL ANTIRESORPTIVE AGENTS: SCIENTIFIC RATIONALE AND PRELIMINARY CLINICAL RESULTS. Musculoskeletal Tumor Society, 2004
- Delloy C, Suratwala S, Lee FY: LACK OF HEALING RESPONSE IN ALLOGRAFT SURGERIES. Musculoskeletal Tumor Society, 2004
- Lee FY et al: RECRUITMENT OF OSTEOCLAST PRECURSOR CELLS BY STROMAL CELL DERIVED FACTOR-1 IN GIANT CELL TUMOR OF BONE. 10th Workshop on Frontiers of Skeletal Biology, Davos, 2004.
- Lee FY, Suratwala, S, Yu J: TREATMENT OF AGGRESSIVE OSTEOLYTIC BENIGN BONE LESIONS WITH TOPICAL ANTIRESORPTIVE AGENTS: PART I. SCIENTIFIC RATIONALE. 10th Workshop on Frontiers of Skeletal Biology, Davos, 2004.
- Lee FY et al: TREATMENT OF AGGRESSIVE OSTEOLYTIC BENIGN BONE LESIONS WITH TOPICAL ANTIRESORPTIVE AGENTS: PART II. PRELIMINARY CLINICAL RESULTS. 10th Workshop on Frontiers of Skeletal Biology, Davos, 2004.
- Lee FY et al: DIAGNOSTIC VALUE AND LIMITATIONS OF 18-FDG PET SCAN FOR CARTILAGINOUS TUMORS OF BONE. 2003 Musculoskeletal Tumor Society Meeting, Chicago, May 2003
- Lee FY et al: ANTI-RESORPTIVE AGENT AS A NOVEL ADJUVANT THERAPY FOR GIANT CELL TUMOR OF BONE. 2003 Musculoskeletal Tumor Society Meeting, Chicago, May 2003.
- Lee FY et al: INDUCTION OF APOPTOSIS IN GIANT CELL TUMOR CELLS. 30th European Symposium on Calcified Tissue, May 2003.
- MA Vitale, JC Choe, AM Sesko, JE Hyman, FY Lee, DP Roye, MG Vitale: THE EFFECT OF LEG LENGTH DISCREPANCY ON HEALTH-RELATED QUALITY OF LIFE: IS THE "2cm RULE" APPROPRIATE? American Academy of Orthopaedic Surgeons New Orleans, LA, 2003
- O Ugwonali, G Lomas, JC Choe, JE Hyman, FY Lee, MG Vitale, DP Roye: EFFECT OF BRACING ON THE QUALITY OF LIFE OF ADOLESCENTS WITH IDIOPATHIC SCOLIOSIS. Scoliosis Research Society, Seattle, WA, 2002
- SK Storer, MG Vitale DE Long, JC Choe, JE Hyman, FY Lee, DP Roye: CORRECTION OF ADOLESCENT IDIOPATHIC SCOLIOSIS USING THORACIC PEDICLE SCREW FIXATION vs. TRADITIONAL HOOK CONSTRUCTS: A SINGLE SURGEON RETROSPECTIVE REVIEW. International Congress on Spinal Surgery Turkey, 2002
- MG Vitale JC Choe, MA Vitale, BD Roye, JE Hyman, FY Lee, DP Roye: PATIENT-BASED OUTCOMES FOLLOWING CLUBFOOT SURGERY: A FIFTEEN YEAR FOLLOW-UP STUDY. American Academy of Orthopaedic Surgeons. Dallas, TX, 2002
- MG Vitale DE Levy, JC Choe, AC Gelijns, AJ Moskowitz, JE Hyman, FY Lee, DP Roye: PEDIATRIC SPINE DEFORMITY: ASSESSING PATIENT OUTCOMES AND QUALITY OF LIFE. International Congress on Spinal Surgery. Turkey, 2002
- MG Vitale, JC Choe, AC Gelijns, AJ Moskowitz, JE Hyman, FY Lee, DP Roye: ASSESSMENT OF HEALTH STATUS IN PATIENTS WITH CEREBRAL PALSY: WHAT IS THE ROLE OF QUALITY OF LIFE MEASURES? International Society for Quality of Life Research. Amsterdam, 2001
- MG Vitale, JC Choe, MW Hwang, RM Bauer, JE Hyman, FY Lee, DP Roye: POSTOPERATIVE USE OF KETOROLAC TROMETHAMINE IN CHILDREN UNDERGOING SCOLIOSIS SURGERY: AN ANALYSIS OF COMPLICATIONS. North American Spine Society, New York, NY, 2002
- Lee FY, Heddon D, Alman B : GRANULOMATOUS FOREIGN BODY REACTION TO METAL WEAR DEBRIS FOLLOWING POSTERIOIR SPINE INSTRUMENTATION FOR SCOLIOSIS. 69th Annual Meeting of American Academy of Orthopaedic Surgeons, Dallas, Texas, 2002.
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