Doctors & other Staff

LeeFrancis Y. Lee, MD, PhD
Curriculum Vitae






CLINICAL INTERESTS
  • Bone and Soft Tissue Tumors in Children and Adults
  • Metastatic Bone Cancers
  • Complex Limb Deformities & Limb Lengthening
  • Children-s Osteoporosis, Syndromes and Bone Disease
  • Congenital and Acquired Hip Disorders
  • Spine Deformity (Scoliosis)
BOARD CERTIFICATIONS
American Board of Orthopaedic Surgery

LICENSURE
New York
New Jersey
Massachusetts

EDUCATION
Fellowship
1998-1999
The Hospital for Sick Children
University of Toronto
Pediatric Orthopaedic Surgery
Clinical Fellow

1997-1998
Harvard Medical School
Mass General & Children’s Hospital
Orthopaedic Oncology
Clinical Fellow
1996 New Jersey Medical School
Newark, New Jersey
Orthopaedic Research Fellow
1995 Mount Sinai School of Medicine
New York, New York
Orthopaedic Research Fellow

Residency
1992-1997
New Jersey Medical School
Newark, New Jersey
Department of Orthopaedic Surgery
1987-1992 Seoul National University Hospital
Seoul, Korea
Department of Orthopaedic Surgery
Graduate
1993
Seoul National University
Orthopaedic Science
Seoul, Korea
M.S., Ph.D.
Medical School
1986
Seoul National University
Seoul, Korea
M.D.
Undergraduate
1982
Seoul National University
Seoul, Korea
B.S.
CURRENT HOSPITAL & ACADEMIC APPOINTMENTS

  • 08/01/1999- 07/31/05
    Assistant Professor
    Department of Orthopaedic Surgery
    Columbia University, New York
  • 08/01/1999 - Present
    Chief of Tumor and Bone Disease Service
    Department of Orthopaedic Surgery
    Columbia University, New York
  • 09/01/2003 - Present
    Director of Center for Orthopaedic Research
    Department of Orthopaedic Surgery
    Columbia University, New York
  • 08/01/2006 - Present
    Associate Professor of Clinical Orthopaedic Surgery
    Columbia University, New York
  • 07/01/2007 - Present
    Vice Chairman for Research
    Department of Orthopaedic Surgery
    Columbia University, New York
  • 07/01/2009 – Present
    Associate Professor or Orthopaedic Surgery with Tenure (Unmodified Title)
    Department of Orthopaedic Surgery, Columbia University, New York
PROFESSIONAL ORGANIZATIONS AND SOCIETIES

  • National Institute of Health (NIH) Grant Reviewer: NIH Skeletal Biology and Skeletal Regeneration Study Section (2007), Special Emphasis Panel (2008), Challenge Grants (2009), Musculoskeletal Tissue Engineering Study Section (2010)
  • American Academy of Orthopaedic Surgeons Leadership Fellow (2007 - Present)
  • American Academy of Orthopaedic Surgeons Research Development (AAOS RDC) Committee (2008 – Present)
  • AAOS Clinician Scientist Development Program Chair (Chicago, IL; 2010)
  • Orthopaedic Research Society Program Committee (2009-2010); Cancer Topic Chair (2010-2012)
  • American Board of Orthopaedic Surgery (ABOS) Field Test  Task Force (2008-Present)
  • New York Orthopaedic Hospital Multidisciplinary Bone Symposium Program Chair (Sep 29th, 2009): Tenure Appointment Scientific Symposium Reception
  • Grant Reviewer, Musculoskeletal Transplantation Foundation (2006 - Present)
  • Grant Reviewer, Orthopaedic Research and Education Foundation (2006 - Present)
  • Member, American Orthopaedic Association (2006 - Present)
  • Member, American Academy of Orthopaedic Surgeon, Evaluation Committee (2005 - Present)
  • Member, American Academy of Orthopaedic Surgeon, Basic Science Evaluation Subcommittee / Basic Science Committee for Orthopaedic In-Training Examination (2004 - Present)
  • Musculoskeletal Tumor Society , U.S.A. (2003 - )
  • Member, American Academy of Orthopaedic Surgeons (2001 - Present)
  • American Medical Association
  • Member, Orthopaedic Research Society (1997 - Present)
  • American Society for Bone and Mineral Research
  • Irving Comprehensive Cancer Center
  • New York Academy of Medicine
  • Member, New York Academy of Science(1996 - Present)
  • International Bone and Mineral Society
  • American Academy of Orthopaedic Surgery, Basic Science Evaluation Subcommitee

RECENT HONORS
  • Tenure Appointment, Department of Orthopaedic Surgery, Columbia University (2009)  
  • 2006-2009 Orthopaedic Research and Education Foundation Career Development Award
  • American Academy of Orthopaedic Surgeons Osteolysis and Implant Wear Symposium Young Investigator Traveling Award (Nov 9-11, 2007)
  • American Academy of Orthopaedic Surgeons Leadership Fellow, 2007
  • Musculoskeletal Transplant Foundation Research Grant Reviewer
  • 2006-2008 Orthopaedic Research and Education Foundation Research Grant Reviewer
  • SNUMC Alumni Association HamChun Award, 2005
  • Orthopaedic Research and Education Foundation Research Grant Award, 2004-2006
  • 2004-2005 American Academy of Orthopaedic Surgeons / Orthopaedic Research and Education Foundation Clinician Scientist Traveling Award
  • 2004-2005 Aircast Foundation Research Grant Award
  • 2002 American Cancer Society /Irving Cancer Center Pilot Research Award
  • Best Specialty Society Paper at the American Academy of Orthopaedic Surgeons, 2001
  • Start-up Research Grant Award, Hospital for Sick Children, Toronto, Canada, 1999
  • National Orthopaedic Surgery Research Fellow Foundation, 1998
  • Annual Resident Research Award, New Jersey Medical School, 1997
  • Young Investigator Award, 5th Biennial International Society for Fracture Repair, 1996
  • American Fracture Association,
  • Resident Research Grant, 1996
  • American Orthopaedic Association-Zimmer Resident Travel Award, 1996
  • American Fracture Association,
  • Resident Research Award, 1996
  • OREF Resident Research Award, 1995
  • Who's Who in Science, New Jersey, U.S.A., 1999.
  • Dictionary of International Biography, 27th Edition, Cambridge, England, 1999
  • Outstanding People of the 20th Century,
RESEARCH GRANTS AND AWARDS (No Conflict of Interest with Industries)

Present Research Support (Principal Investigator: Francis Y. Lee, M.D.)

  • National Institute of Health (NIH)
    Role: Principal Investigator
    National Institute of Biomedical Imaging and Biomedical Engineering (NIBIB)
    Title: Mechanobiological Mechanism of Inflammatory Bone Loss
    Period: June 1st, 2007 - May 31st, 2011

  • National Institute of Health (NIH)
    Role: Principal Investigator
    National Institute of Arthritis, Musculoskeletal and Skin Disorders (NIAMS)
    Title: ERK Signaling in Inflammatory Bone Loss
    Period: Feb 2009 – Jan 2013

  • AO Foundation (Lou Amorosa, MD Resident PI/ Francis Y. Lee, MD Faculty PI               
    Title: Segmental Bone Defect Healing using Anatomically Matched Scaffold  
    Period: 2009-2010

  • Orthopaedic Research and Education Foundation (OREF) Grant
    Role: Principal Investigator
    Career Development Award (Peer-Reviewed)
    Period: July 1st, 2006 - June 30th, 2009

  • Columbia University Venture Fund
    Role: Principal Investigator
    Title: Innovative Sarcoma Research (Stem Cell-based Delivery of siRNA to Sarcoma Cells)
    Period: January 1st, 2007 - December 31st, 2007

  • Unrestricted Research Grant (Donor: David E. Shaw, Ph.D)
    Role: Principal Investigator
    Period: November 25, 2005 - Present

  • Orthopaedic Research and Education Foundation Grant
    Role: Mentor (Co-PI)
    Resident Research Grant (PI: Sam K. Cho, M.D., Orthopaedic Resident)
    Title: The role of ERK signaling in titanium-induced inflammatory bone loss
    Period: July 1st, 2007 - June 30th, 2008

  • Orthopaedic Science Research Foundation (OSRF)
    Role: Principal Investigator
    Title: In vivo Biomolecular Imaging Core Grant
    Period: July 1st, 2007 - June 30th, 2010

Past Research Support (Principal Investigator: Francis Y. Lee, M.D.)

  • Orthopaedic Research & Education Foundation
    Role: Principal Investigator
    Resident Research Award / Research Grant (Peer-Reviewed)
    Title: The fate of chondrocyte during fracture healing
    Period: January 1st, 1995 - December 31st, 1995

  • American Fracture Association
    Role: Principal Investigator
    Title: The effect of nicotine on fracture healing
    Period: July 1st, 1996 - December 31st, 2006

  • National Orthopaedic Surgery Fellowship Foundation
    Role: Principal Investigator
    Title: The effect of rhBMP-2 on allograft fracture repair
    Period: January 1st, 1998 - June 30th, 1998

  • Hospital for Sick Children Start-up Research Grant
    Role: Principal Investigator
    Title: Vitamin D3 pathway activation in chondrosarcoma
    Period: January 1st, 1999 - June 30th, 1999

  • American Cancer Society Pilot Award
    Role: Principal Investigator
    Title: Molecular Pathways in Cartilage Tumors
    Period: January 1st, 2002 - December 31st, 2002

  • Woman-at-Risk, Breast Cancer Program
    Role: Principal Investigator
    Title: Molecular mechanisms of osteolytic metastatic breast cancer
    Period: July 1st, 2002 - June 30th, 2003

  • Howmedica, Rutherford, NJ
    Role: Principal Investigator
    Title: Developing Novel Implants
    Period: January 1st, 2003 - June 30th, 2004

  • Aircast Foundation Research Grant
    Role: Principal Investigator
    Title: Targeting Cell Survival Genes of Chondrosarcoma (Peer Reviewed)
    Period: January 1st, 2005 - December 31st, 2006

  • Musculoskeletal Transplant Foundation
    Role: Principal Investigator
    Title: The Beneficial Effect of Topical Bisphosphonate on Trabecular Bone Allograft
    Period: Jan 1, 2005 - Dec 31, 2005

  • Orthopaedic Research and Education Foundation
    Role: Principal Investigator
    Title: SDF-1 Regulation in Osteoclastogenesis
    Period: July 1, 2004-June 30, 2006

  • TissueGene, Inc., Gaithersburg, MD
    Role: Principal Investigator
    Sponsored Research Grant through Columbia University
    Title: Gene Expression Profiling of Cartilage
    Period: 2003-2006

  • Orthopaedic Research and Education Foundation Grant
    Role: Mentor
    Resident Research Grant (PI: Sanjeev Suratwala, M.D., Orthopaedic Resident)
    Title: The role of topical bisphosphonate on orthopaedic implants
    Period: Jan 1st, 2006 - June 30th, 2006

  • Orthopaedic Research and Education Foundation Grant
    Role: Mentor
    Resident Research Grant (PI: Steve Storer, M.D., Orthopaedic Resident)
    Title: The role of bisphosphonate on allograft bone healing
    Period: Jan 1st, 2004 - June 30th, 2004

  • Orthopaedic Science Research Foundation
    Role: Center Director
    Center for Orthopaedic Research Infrastructure Grant
    Period: 2004 - 2006
PEER-REVIEWED PUBLICATIONS  (In Chronological Order)
  1. Kim YM, Lee SH, Lee FY, Koo KH and Cho KH: Morphologic and biomechanical study of avascular necrosis of the femoral head. Orthopaedics 14:1111-1116, 1991.
  2. Seong SC, Matsumura T, Lee FY, Whelan MC, Li XQ and Trippel SB: Insulin-like growth factor I regulation of Swarm rat chondrosarcoma chondrocytes in culture. Experimental Cell Research 211:238-244, 1994.
  3. Harten RD, Lee FY, Hurowitz EJ, Arakal RJ, Zimmerman MC, and Behrens FF: Regional and temporal changes in the acoustic properties of fracture callus in secondary bone healing. Journal of Orthopaedic Research, 15(4):570-576, 1997.
  4. Lee FY*, Hazan EJ, Kloen P, Mankin HJ.  Reconstruction of shoulder joint using osteoarticular acetabular allograft after scapular resection.  A report of two cases.  Clinical Orthopaedics and Related Research, 357: 116-121, 1998.
  5. Benevenia J, Lee FY, Buechel FF, Parsons JR: Aggressive Granulomatous Lesion following Total Knee Replacement Arthroplasty. Journal of Biomedical Materials Research Applied Biomaterials, 43(4):473-477, 1998.
  6. Lee FY*, Gebhardt MC, Keel SB, Rosenthal DI.  Orthopaedic-Pathology-Radiology Conference.  A discrete soft tissue mass in the distal thigh of 29-year–old male.  Clinical Orthopaedics and Related Research, 357: 247-250, 1998.
  7. Lee FY*, Behrens FF, DeFouw DO, and Einhorn TA: Programmed Removal of Chondrocytes During Enchondral Fracture Healing. Journal of Orthopaedic Research, 16(1), 144-149, 1998.
  8. Lee FY*, Rho JY, Harten R, Parsons JR, Behrens FF.  Micromechanical Properties of Primary Spongiosa and Epiphyseal Trabecular Bone.  Journal of Pediatric Orthopaedics, 18: 582-585, 1998.
  9. Lee FY*, Montgomery M, Hazan EJ, Keel SB, Mankin HJ, Kattapuram S.  Recurrent giant cell tumor presenting as an isolated soft Tissue mass.  A report of four cases.  Journal of Bone and Joint Surgery (Am), 81A: 703-707, 1999.
  10. Lee FY*, Mankin HJ, Gebhardt MC, Springfield D, Fondren G, Jennings LC, Rosenberg A.  Outcome analysis of chondrosarcoma. Journal of Bone and Joint Surgery (Am) 81A: 326-338, 1999.
  11. Margau R, Babyn P, Cole W, Smith C, Lee F: MR imaging of simple bone cysts in children: not so simple. Pediatric Radiology, 30:551-557, 2000.
  12. Ramappa AJ, Lee FY, Tang P, Carlson JR, Gebhardt MC, Mankin HJ: Chondroblastoma of bone. Journal of bone and Joint Surgery, 82A:1140-1145, 2000.
  13. Lee FY*, Hazan EJ, Gebhardt MC, Mankin HJ.  An experimental model for allograft fracture repair.  Journal of Orthopaedic Research, 18:303-306, 2000.
  14. Patari S, Lee FY*, Behrens FF: Coronal split fracture in a partially fused physis in the proximal tibia. Journal of Pediatric Orthopaedics 21:451-455, 2001.
  15. Lee FY*, Keel SB, Gebhardt MC, Rosenthal DI: Intra-articular lipoma with osteochondral metaplasia in the knee joint. Skeletal Radiology, 30:230-233, 2001.
  16. Ahmad CS, Lee FY*: An all arthroscopic soft tissue balancing technique for lateral patellar instability. Arthroscopy, 17:555-557, 2001.
  17. Osgood G, Lee FY*, Parisien MV, Ruzal-Shapiro C: Magnetic resonance imaging depiction of tight iliotibial band in melorheostosis associated with severe external rotation deformity, limb shortening and patellar dislocation in planning surgical correction. 2002; Skeletal Radiology, 31:49-52.
  18. Lee FY*, Zawadsky M, Parisien M, Ho M, M VVVS, Jayaraman T, Dick HM: A novel translocation t(9;12)(q22;q24) in secondary chondrosarcoma arising from hereditary multiple exostosis. Cancer Genetics and Cytogenetics. 2002; 132(1)68-70.
  19. Lee FY*, Storer SK, Hazan EJ, Gebhardt MC, Mankin HJ: Repair of bone allograft fracture using bone morphogenetic protein-2 in an animal experimental model. Clinical Orthopaedics and Related Research, April, 397:119-126, 2002.
  20. Lee FY*, Chapman C: In Situ Pinning of the Hip for Stable Slipped Capital Femoral Epiphysis on a Radiolucent Table: Modification of Percutaneous Pinning Technique Using a Fracture Table. Journal of Pediatric Orthopaedics, 23(1): 27-29, 2003
  21. MG Vitale, JC Choe, MW Hwang, RM Bauer, JE Hyman, FY Lee, DP Roye: Postoperative Use of Ketorolac Tromethamine in Children Undergoing Scoliosis Surgery. The Spine Journal, 2003; 3:55-62.
  22. Ugwanali O, Vitale MG, Hyman JE, Lee FY, Roye DP: Effect of bracing on the quality of adolescent with idiopathic scoliosis. The Spine Journal, March, 4:254-260, 2004.
  23. Lee FY*, Hornicek FJ, Dick HM, Mankin HJ: Synovial chondromatosis of the foot. Clinical Orthopaedic and Related Research, April, 423:186-190, 2004.
  24. Roposch A, Bhaskar AR, Lee F, Adedapo S, Mousny M, Alman BA:  Orthopaedic manifestations of Brachmann-de Lange syndrome: a report of 34 patients. Journal of Pediatric Orthopaedics, 2004;13 (B):118-122.
  25. Lee FY*, Yu John, Parisien MV, Chang SS, Fawaaz R: Diagnostic accuracy and limitations of positron emission tomography for the diagnosis of cartilaginous tumors. Journal of Bone and Joint Surgery, 2004 Dec;86-A(12):2677-85. 2004.
  26. Chang SS, Suratwala S, Jung KM, Doppelt J, Zhang HJ, Blaine TA, Kim TW, Winchester RJ, Lee FY*: Bisphosphonate may reduce recurrence in GCT by inducing apoptosis. Clinical Orthopaedics and Related Research, September, 426:103-109, 2004.
  27. Delloye C, Suratwala S, Valentin-Opran A, Cornu O, Lee FY: Treatment of Allograft Nonunions with Recombinant Human Bone Morphogenetic Proteins (rhBMP): Early Clinical Results. Acta Orthopaedica Belgica, 2004 70:591-597.
  28. Lee FY*, Scoeb JS, Yu J, Dick HM: Operative lengthening of the humerus: Indications, benefits and complications. Journal of Pediatric Orthopaedics, September, 2005, 25: 613-616.
  29. Yoon AJ, Marisien M, Feldman F, Lee FY: Extranodal Rosai-Dorfman disease of bone, subcutaneous tissue and paranasal simus mucosa: Case report and review of the literature. Skeletal Radiology, 2005 Oct;34(10):653-7.
  30. Vitale MG, Choe JC, Vitale MA, Lee FY, Hyman JE, Roye DP Jr: Patient-based outcomes following clubfoot surgery: a 16-year follow-up study. Journal of Pediatric Orthopaedics. 2005 Jul-Aug;25(4):533-8.
  31. Storer SK, Vitale MG, Hyman JE, Lee FY, Choe JC, Roye DP Jr: Correction of adolescent idiopathic scoliosis using thoracic pedicle screw fixation versus hook constructs. Journal of Pediatric Orthopaedics. 2005 Jul-Aug;25(4):415-9.
  32. Liao T, Yurgelun M, Chang SS, Murakami K, Zhang HZ, Parisien MV, Blaine TA, Kim W, Winchester RJ, Lee FY*: Recruitment of osteoclast precursors by stromal cell derived factor-1 in giant cell tumor of bone. Journal of Orthopaedic Research, 2005 Jan;23(1):203-9.
  33. Blaine TA, Kim YS, Voloshin I, Chen D, Murakami K, Chang SS, Winchester R, Lee FY, O'keefe RJ, Bigliani LU: The molecular pathophysiology of subacromial bursitis in rotator cuff disease. J Shoulder Elbow Surg. 2005 Jan-Feb;14(1 Suppl S):84S-89S.
  34. Vitale MG, Roye EA, Choe JC, Hyman JE, Lee FY, Roye DP Jr: Assessment of health status in patients with cerebral palsy: what is the role of quality-of-life measures? Journal of Pediatric OrthopaeDICS. 2005 Nov-Dec;25(6):792-7.
  35. Yu J, Chang SS, Suratwala S, Chung W, Abdelmessieh P, Lee HJ, Yang J, Lee FY*: Zoledronate induces apoptosis in stromal cells of unicameral bone cyst. Journal of Orthopaedic Research, 2005 May 24; 23(5):1004-12
  36. Lee FY*, Kim DW, Karmin JA, Hong D, Chang SS, Fujisawa M, Takayanagi H, Bigliani LU, Blaine TA, Lee HJ: mu -calpain regulates RANKL-supported osteoclastogenesis via NF-kappa B activation in raw 264.7 cells. Jouranl of Biological Chemistry. 2005 Jun 13; 280(33):29929-36.
  37. Vitale MA, Choe JC, Sesko AM, Hyman JE, Lee FY, Roye DP Jr, Vitale MG: The effect of limb length discrepancy on health-related quality of life: is the '2 cm rule' appropriate? Journal of Pediatric Orthopaedics B. 2006 Jan;15(1):1-5.
  38. Kim DW, Lee HJ, Karmin J, Lee SE, Chang SS, Tolchin B, Lin S, Cho SK, Kwon A, Ahn JM, and Lee FY*: Mechanical Loading Differentially Regulates Membrane-Bound and Soluble RANKL Availability in MC3T3-E1 Cells. Annals of New York Academy of Science, April 2006, Vol 1068, pp568-572.
  39. Kim YS, Bigliani LU, Fujisawa M, Murakami K, Chang SS, Lee HJ, Lee FY, Blaine TA: Stromal cell-derived factor 1 (SDF-1, CXCL12) is increased in subacromial bursitis and downregulated by steroid and nonsteroidal anti-inflammatory agents. Journal of Orthopaedic Research. 2006 Jun 15, 24: 1756-64.
  40. Lee FY*, Sinicropi S, Vitale MG, Lee FS, Roye DP, Choi IH: Treatment of congenital pseudarthrosis of tibia with recombinant human bone morphogenetic protein-7: A prospective study. Journal of Bone and Joint Surgery, 2006 Mar;88(3):627-33
  41. Lowenstein JE, Matsumoto H, Vitale MG, Weidenbaum M, Gomez JA, Lee FY, Hyman JE, Roye DP Jr: Coronal and sagittal plane correction in adolescent idiopathic scoliosis: A comparison between all pedicle screw versus hybrid thoracic hook lumbar screw constructs. Spine. 2007 Feb 15;32(4):448-52.
  42. Kim DW, Seo SW, Cho S, Chang SS, Lee HW, Lee SE, Block JA, Hei TK, Lee FY*: Targeting of cell survival genes using small interfering RNAs (siRNAs) enhances radiosensitivity of Grade II chondrosarcoma cells. Journal of Orthopaedic Research, March 7th 2007, 25(6):820-8.
  43. Minematsu H, Seo S, Adelmir A, Lee FY*: CALCINEURIN/NFATC1 AXIS REGULATES UHMWPE WEAR PARTICLE-INDUCED CYTOKINE EXPRESSION IN MACROPHAGES. The Annals of New York Academy of Science. 2007 Nov;1117:143-50.
  44. Seo SW, Adelmir A, Minematsu H, Lee FY*: ERK SIGNALING REGULATES M-CSF EXPRESSION INDUCED BY TITANIUM NANOPARTICLES IN MC3T3-E1 MURINE CALVARIAL PRE-OSTEOBLASTIC CELLS. The Annals of New York Academy of Science. 2007 Nov;1117:151-8.
  45. Celil Aydemir AB, Lee S, Won Kim D, Gardner TR, Prince D, Mok Ahn J,  Lee FY*: Calcineurin/NFATc axis mediated fluid shear stress-induced COX-2 expression in human mesenchymal cells. The Annals of New York Academy of Science. 2007, Nov;1117:138-42.
  46. Tuan RS, Lee FY, Konttinen YT, Wilkinson JM, Smith RL: What are the local and systemic biologic reactions and mediators to wear debris, and what host factors determine or modulate the biologic response to wear particles? Journal of American Academy of Orthopaedic Surgeons. 2008. 16(S):42-48.
  47. Sanjeev Suratwala, Samuel K. Cho, Jonathan Van Rattle, Sang H Park, Sung W Seo, Seong-Sil chang, Thomas R. Gardner, Lee, FY*: Enhancement of periprosthetic bone quality with topical hydroxyapatite-bisphosphonate composite: An Experimental Study. The Journal of Bone and Joint Surgery 2008. 90A (10):2189-2195.
  48. Seo SW, Cho SK, Storer SK, Lee FY. Zoledronate reduces unwanted bone resorption in intercalary bone allografts. Int Orthop. 2009 Apr 3.
  49. Seo SW, Lee D, Minematsu H, Kim AD, Shin M, Cho SK, Kim DW, Yang J, Lee FY. Targeting extracellular signal-regulated kinase (ERK) signaling has therapeutic implications for inflammatory osteolysis. Bone. 2009 Nov 4. [Epub ahead of print] PubMed PMID: 19895919.
  50. Aydemir AB, Minematsu H, Gardner TR, Kim KO, Ahn JM, Lee FY. Nuclear factor of activated T cells mediates fluid shear stress- and tensile strain-induced Cox2 in human and murine bone cells. Bone. 2009 Sep 11. [E-PUB] PubMed PMID: 19748606.
  51. Cadet ER, Vorys GC, Rahman R, Park SH, Gardner TR, Lee FY, Levine WN, Bigliani LU, Ahmad CS. Improving bone density at the rotator cuff footprint increases supraspinatus tendon failure stress in a rat model. Journal of Orthopaedic Research. 2009 Sep 9. PubMed PMID: 19743506
  52. Kim DW, Kim KO, Shin MJ, Ha JH, Seo SW, Yang J, Lee FY. siRNA-based targeting  of antiapoptotic genes can reverse chemoresistance in P-glycoprotein expressing chondrosarcoma cells. Molecular Cancer. 2009 May 15;8:28.
  53. Seo SW, Cho SK, Storer SK, Lee FY. Zoledronate reduces unwanted bone resorption in intercalary bone allografts. International Orthopaedics. 2009 Apr 3.
  54. Mills J, Matos T, Charytonowicz E, Hricik T, Castillo-Martin M, Remotti F, Lee FY, Matushansky I. Characterization and comparison of the properties of sarcoma cell lines in vitro and in vivo. Human Cell. 2009 Nov;22(4):85-93. PubMed PMID: 19874397.

BOOKS AND CHAPTERS

  • Carol Morris, Lee FY and Gebhardt MC. Benign Bone Tumors, Chapter, Operative Orthopaedic Surgery, Ed. Chapman M, Williams and Wilkins, 2000.
  • Lee FY and Lee HK. Basic science in musculoskeletal tumor, Chapter, Musculoskeletal Oncology, Ed. Lee HK, 1996, Korea.
  • Hyman J, Lee FY, Roye DP. Orthopaedic Surgery, Chapter, Pediatric Secrets, Ed, 200.
  • Seo SW, F Remotti, Lee FY: Chondrosarcoma, Orthopaedic Knowledge Update, Musculoskeletal Oncology.
  • Seo SW, Moon YL, Lee FY: Benign Cystic Lesions. Essentials of Orthopaedic Surgery, (In Preparation)
  • AAOS Comprehensive Orthopaedic Review. Section 1. Basic Science (2009) American Academy of Orthopaedic Surgeon
  • Self Assessment Examination, Basic Science. American Academy of Orthopaedic Surgeons

 

 
 

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